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Bioinformatics Algorithm

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There are two approaches, exhaustive and heuristic approaches, used in multiple sequence alignment. The exhaustive alignment method includes searching all possible aligned positions simultaneously. This…

UPGMA (unweighted pair group method with arithmetic mean) The UPGMA is the simplest distance-matrix method, and it employs sequential clustering to build a rooted phylogenetic…

Pairwise Algorithm A Pairwise Algorithm is an algorithmic technique with its origins in Dynamic programming. Pairwise algorithms have many uses including comparing a protein profile…

Probalign is a sequence alignment tool that calculates a maximum expected accuracy alignment using partition function posterior probabilities. Base pair probabilities are estimated…