Multi-target directed ligands are drugs with two or more pharmacophores, which are structurally overlapping, or separated, by a spacer, in a…
In genetics, a dynamic mutation is an unstable heritable element where the chances of expression of a mutant phenotype is a function of…
Homology directed repair (HDR) is a naturally occurring nucleic acid repair system that can be used to modify genomes in many organisms,…
Non-Homologous End Joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. NHEJ is known as “non-homologous” because the break…
Transcription Activator-Like Effector Nucleases (TALEN) is restriction enzymes that can be engineered to cut specific sequences of DNA. They are made by fusing…
The CRISPR-Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages and provides…
Forensic science is a key instrument for the detection or investigation of crime and the conduction of justice by providing…
Biopolymers are chain-like molecules made up of repeating chemical blocks and can be very long in length and are produced by…
A monoclonal antibody (mAb or moAb) is an antibody made by cloning a unique white blood cell or a type of protein made in the laboratory that can bind…
Cas12 is a compact and efficient enzyme that produces staggered cuts in dsDNA. Cas12 processes its own guide RNAs, leading to increased multiplexing…