ChEMBL is an open data database having binding, functional and ADMET information for a large number of drug-like bioactive compounds.…
Scientists know that a mutation or any change in a particular gene’s DNA may present to a certain disease. However,…
Serial analysis of gene expression (SAGE) is a powerful technique that uses mRNA from a particular sample to generate complementary…
Types and Functions of RNA The three main, most well-known and most commonly studied are messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA), which…
RNA is a single stranded structure and is made of ribonucleotides that are linked by phosphodiester bonds. A ribonucleotide in the RNA…
A DNA sequence that is involved in the regulation of genes is called Transcription Factor Binding Site. It has binding…
Understanding the role of individual components in a biological system is an important step to elucidate or predict its behavior.…
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can…
DNA damage occurs continuously as a result of many factors including intracellular metabolism, replication, and exposure to genotoxic agents, such as ionizing…
An origin of replication is a sequence of DNA at which replication is started on a chromosome, plasmid or virus. For small DNAs, including…